Publications
2024
Reyes Ballista JM, Hoover AJ, Noble JT, Acciani MD, Miazgowicz KL, Harrison SA, Tabscott GAL, Duncan A, Barnes DN, Jimenez AR, Brindley MA. Chikungunya Virus Release is Reduced by TIM-1 Receptors Through Binding of Envelope Phosphatidylserine. bioRxiv. 2024 Jan 26:2024.01.25.577233. PMID: 38329121, accepted JVirol June 12,2024
Rhagunath G, Abbott EH, Marin M, Wu H, Reyes Ballista JM, Brindley MA, Melikyan GB. Disruption of transmembrane phosphatidylserine asymmetry by HIV-1 incorporated SERINC5 is not responsible for virus restriction. Biomolecules 2024 May 10: 14(5), 570. PMID: 38785977
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2023
Reyes Ballista JM*, Miazgowicz KL*, Acciani MD, Jimenez AR, Belloli RS, Havranek KE, Brindley MA. Chikungunya virus entry and infectivity is primarily facilitated through cell line dependent attachment factors in mammalian and mosquito cells. Front Cell Dev Biol. 2023 Jan 20;11:1085913. PMID: 36743418 (*co-first author)
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Chan JF, Huang X, Hu B, Chai Y, Shi H, Zhu T, Yuen TT, Liu Y, Liu H, Shi J, Wen L, Shuai H, Hou Y, Yoon C, Cai JP, Zhang AJ, Zhou J, Yin F, Yuan S, Zhang BZ, Brindley MA, Shi ZL, Yuen KY, Chu H. Altered host protease determinants for SARS-CoV-2 Omicron. Sci Adv. 2023 Jan 20;9(3):eadd3867. PMID: 36662861
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Zhang Y, York J, Brindley MA, Nunberg JH, Melikyan GB. Fusogenic Structural Changes in Arenavirus Glycoproteins are Associated with Viroporin Activity. PLoS Pathog. 2023 Jul 26;19(7):e1011217. PMID: 37494374
2022
Sheikh MO, Capicciotti CJ, Liu L, Praissman JL, Mead DG, Brindley MA, Willer T, Campbell KP, Moremen KW, Wells L, Boons GJ. Cell Surface Glycan Engineering Reveals that Matriglycan Alone can Recapitulate Dystroglycan Binding and Function. Nat Commun. 2022 Jun 24;13(1):3617. PMID: 35750689
Tesla B, Powers JS, Barnes Y, Lakhani S, Acciani MD, Brindley MA. Temperate conditions limit Zika virus genome replication. J Virol. 2022 May 25;96(10): e0016522. PMID: 35467365
Au WY, Ye C, Briner SL, Suarez GD, Han J, Xu X, Park JG, Brindley MA, Martinez-Sobrido L, Cheung PP. Systematic comparison between BNT162b2 and CoronaVac in the seroprotection against SARS-CoV-2 Alpha, Beta, Gamma, and Delta variants. J Infect.
2022 Mar 1;S0163-4453(22)00123-2. PMID: 35245585
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Shuai H, Chan JF, Hu B, Chai Y, Yuen TT, Yin F, Huang X, Yoon C, Hu JC, Liu H, Shi J, Liu Y, Zhu T, Zhang J, Hou Y, Wang Y, Lu L, Cai JP, Zhang AJ, Zhou J, Yuan S, Brindley MA, Zhang BZ, Huang JD, To KK, Yuen KY, Chu H. Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 Omicron. Nature. 2022 Jan 21. PMID: 35062016
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2021
Havranek KE, Reyes Ballista JM, Hines KM*, Brindley MA*. Untargeted lipidomics of vesicular stomatitis virus infected cells and viral particles. Viruses. 2021 Dec 21;14(1):3. PMID: 35062207 (*co-corresponding authors)
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Paschall AV, Ozdilek A, Briner SL, Brindley MA, Avci F. Modulation of immunosuppressant drug treatment to improve SARS-CoV-2 vaccine efficacy in mice. Vaccine. 2021 Dec 31:S0264-410X(21)01666-2. PMID: 34991929
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Acciani MD, Lay Mendoza MF, Havranek KE, Duncan AM, Iyer H, Linn OL, Brindley MA. Ebola Virus Requires Phosphatidylserine Scrambling Activity for Efficient Budding and Optimal Infectivity. J Virol. 2021 Sep 27;95(20):e0116521. PMID: 34319156
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An D, Li K, Rowe DK, Diaz MCH, Griffin EF, Beavis AC, Johnson SK, Padykula I, Jones CA, Briggs K, Li G, Lin Y, Huang J, Mousa J, Brindley M, Sakamoto K, Meyerholz DK, McCray PB Jr, Tompkins SM, He B. Protection of K18-hACE2 mice and ferrets against SARS-CoV-2 challenge by a single-dose mucosal immunization with a parainfluenza virus 5-based COVID-19 vaccine. Sci Adv. 2021 Jul 2;7(27):eabi5246. PMID: 34215591
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Reitmayer CM, Pathak AK, Harrington LC, Brindley MA, Cator LJ, Murdock CC. Sex, age, and parental harmonic convergence behavior affect the immune performance of Aedes aegypti offspring. Commun Biol. 2021 Jun 11;4(1):723. PMID: 34117363
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Brindley MA. mSphere of Influence: Apoptotic Mimicry and Virus Entry. mSphere. 2021 Jan 27;6(1). PMID: 33504657
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Chu H, Hu B, Huang X, Chai Y, Zhou D, Wang Y, Shuai H, Yang D, Hou Y, Zhang X, Tsz-Tai Yuen H, Cai JP, Zhang J, Zhou J, Yuan S, To K, Chan IHY, Sit KY, Chi-Chung Foo D, Yu-Hong Wong I, Tsui-Lin Ng A, Cheung TT, Law S, Au WK, Brindley MA, Chen Z, Kok KH, Chan J. Host and viral determinants for efficient SARS-CoV-2 infection of the human lung. Nat Commun. 2021 Jan 8;12(1):134. PMID: 33420022
2020
Havranek KE, Jimenez AR, Acciani MD, Lay Mendoza MF, Reyes Ballista JM, Diaz DA, Brindley MA. SARS-CoV-2 Spike Alternations Enhance Pseudoparticle Titers and Replication-Competent VSV-SARS-CoV-2 Virus. Viruses. 2020 Dec 18; 12(12). PMID: 33353101
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Lay Mendoza MF, Acciani MD, Levit CN, Santa Maria C, Brindley MA. Monitoring viral entry in real-time using a luciferase recombinant vesicular stomatitis virus producing SARS-CoV-2, EBOV, LASV, CHIKV, and VSV glycoproteins. Viruses. 2020 Dec 17; 12(12).
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Zhao P, Praissman JL, Grant OC, Cai Y, Xiao T, Rosenbalm KE, Aoki K, Kellman BP, Bridger R, Barouch DH, Brindley MA, Lewis NE, Tiemeyer M, Chen B, Woods RJ, Wells L. Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor. Cell Host Microbe. 2020 Aug 24:S1931-3128(20)30457-1. PMID: 32841605
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Ferreira PG, Tesla B, Horácio ECA, Nahum LA, Brindley MA*, de Oliveira Mendes TA*, Murdock CC*. Temperature Dramatically Shapes Mosquito Gene Expression With Consequences for Mosquito-Zika Virus Interactions. Front Microbiol. 2020 Jun 12;11:901. PMID: 32595607
(*co-corresponding authors)
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2018
Willard KA, Elling C, Stice SL, Brindley MA. The oxysterol 7-ketocholesterol reduces Zika virus titers in Vero cells and human neurons. Viruses. 2018 Dec 30;11(1). PMID 30598036
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Willard KA*, Alston JT*, Acciani M, Brindley MA. Identification of residues in Lassa virus glycoprotein subunit 2 that are critical for protein function. Pathogens. 2018 Dec 26;8(1). PMID 30587764 (*authors contributed equally)
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Goodfellow FT, Willard KA, Wu X, Scoville S, Stice SL*, Brindley MA*. Strain dependent consequences of Zika virus infection and differential impact on neural development. Viruses. Viruses. 2018 Oct 9;10(10). PMID 30304805 (*co-corresponding authors)
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Tesla B, Demakovsky L, Packiam H, Mordecai EA, Rodriguez AD, Bonds MH, Brindley MA, Murdock CC. Estimating the effects of variation in viremia on mosquito susceptibility, infectiousness, and R0 of Zika Aedes aegypti. PLoS Negl Trop Dis. 2018 Aug 22;12(8). PMID 30133450
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Tesla B, Demakovsky L, Mordecai EA, Ryan SJ, Bonds MH, Ngonghala CN, Brindley MA, Murdock CC. Temperature drives Zika virus transmission: evidence from empirical and mathematical models. Proc Biol Sci. 2018 Aug 15;285(1884). PMID 30111605
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Evans MV, Shiau J, Solano N, Brindley MA, Drake JM, Murdock CC. Carry-over effects of urban larval environments on the transmission potential of dengue-2 virus. Parasit Vectors. 2018 Jul 17;11(1):426. PMID: 30016993.
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Ke Z, Strauss JD, Hampton CM, Brindley MA, Dillard RS, Leon F, Lamb KM, Plemper RK, Wright ER. Promotion of virus assembly and organization by the Measles virus matrix protein. Nat Commun. 2018 Apr 30;9(1):1736. PMID: 29712906
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Herrlinger SA, Shao Q, Ma L, Brindley M, Chen JF. Establishing mouse models for Zika virus-induced neurological disorders using intracerebral injection strategies: embryonic, neotatal, and adult. J Vis Exp. 2018 Apr 26;(134). PMID 29757270
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2017
Willard KA*, Demakovsky L*, Tesla B, Goodfellow FT, Stice SL, Murdock CC, Brindley MA. Zika virus exhibits lineage-specific phenotypes in cell culture, in Aedes aegypti mosquitoes, and in an embryo model. Viruses. 2017 Dec 16;9(12). PMID: 29258204 (*authors contributed equally)
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Shao Q, Herrlinger S, Zhu YN, Yang M, Goodfellow FT, Stice SL, Qi XP, Brindley MA, Chen JF. The African Zika virus MR-766 is more virulent and causes more severe brain damage than current Asian lineage and Dengue virus. Development. 2017 Nov 15;144(22):4114-4124 PMID: 28993398
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Acciani M*, Alston JT*, Zhao G, Reynolds H, Ali AM, Xu B, Brindley MA. Mutational analysis of Lassa virus glycoprotein highlights regions required for alpha-dystroglycan utilization. J Virol. 2017 Aug 24;91(18). PMID: 28679759 (*authors contributed equally)
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2016
Shao Q, Herrlinger S, Yang SL, Lai F, Moore JM, Brindley MA, Chen JF. Zika virus infection disrupts neurovascular development and results in postnatal microcephaly with brain damage. Development. 2016 Nov 15;143(22):4127-4136. PMID: 27729407
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Goodfellow FT, Tesla B, Simchick G, Zhao Q, Hodge T, Brindley MA*, Stice SL. Zika Virus Induced Mortality and Microcephaly in Chicken Embryos. Stem Cells Dev. 2016 Nov 15;25(22):1691-1697. PMID: 27627457 (*corresponding author) Featured cover article- one of the most cited articles from the journal in 2016
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2015
Brindley MA*, Chaudhury S*, Plemper RK. Measles Virus Glycoprotein Complexes Preassemble Intracellularly and Relax during Transport to the Cell Surface in Preparation for Fusion. J Virol. 2015 Jan 15;89(2):1230-41. PMID: 25392208 (*authors contributed equally) Featured article
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2014
Brindley MA, Plattet P, Plemper RK. Efficient replication of a paramyxovirus independent of full zippering of the fusion protein six-helix bundle domain. Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):E3795-804. PMID: 25157143
Kiss G, Chen X, Brindley MA, Campbell P, Afonso CL, Ke Z, Holl JM, Guerrero-Ferreira RC, Byrd-Leotis LA, Steel J, Steinhauer DA, Plemper RK, Kelly DF, Spearman PW, Wright ER. Capturing Enveloped Viruses on Affinity Grids for Downstream Cryo-Electron Microscopy Applications. Microsc Microanal. 2014 Feb;20(1):164-74. PMID: 24279992
2013
Brindley MA*, Suter R*, Schestak I, Kiss G, Wright E, Plemper RK. A stabilized headless measles virus attachment protein stalk efficiently triggers membrane fusion. J Virol. 2013 Aug 21. PMID: 23966411 (*authors contributed equally)
Tahara M, Ohno S, Sakai K, Ito Y, Fukuhara H, Komase K, Brindley M, Rota P, Plemper R, Maenaka K, and Takeda M. The receptor-binding site of the measles virus hemagglutinin protein itself constitutes a conserved neutralizing epitope. J Virol. 2013 Mar;87(6):3583-6. PMID: 23283964
Tahara M, Ito Y, Brindley MA, Ma X, He J, Xu S, Fukuhara H, Sakai K, Komase K, Rota PA, Plemper RK, Maenaka K, Takeda M. Functional and structural characterization of neutralizing epitopes of measles virus hemagglutinin protein. J Virol. 2013 Jan; 87(1):666-75. PMID: 23115278
Ader N, Brindley M, Avila M, Orvell C, Horvat B, Hiltensperger G, Schneider-Schaulies J, Vandevelde M, Zurbriggen A, Plemper RK, Plattet P. Active membrane fusion triggering mechanism by morbillivirus attachment protein. J Virol. 2013 Jan;87(1):314-26. PMID: 23077316
2012
Brindley MA, Takeda M, Plattet P, Plemper RK. Triggering the measles virus membrane fusion machinery. Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):E3018-27. PMID: 23027974
Ader N, Brindley MA, Avila M, Origgi FC, Langedijk JP, Orvell C, Vandevelde M, Zurbriggen A, Plemper RK, Plattet P. Structural rearrangements of the central region of the morbillivirus attachment protein stalk domain trigger F protein refolding for membrane fusion. J Biol Chem. 2012 May 11;287(20):16324-34. PMID: 22431728
2011
Plemper RK, Brindley MA, Iorio RM. Structural and mechanistic studies of measles virus illuminate paramyxovirus entry. PLoS Pathog. 2011 Jun;7(6). PMID: 21655106 review
Kondratowicz AS, Lennemann NJ, Sinn PL, Davey RA, Hunt CL, Moller-Tank S, Meyerholz DK, Rennert P, Mullins RF, Brindley M, Sandersfeld LM, Quinn K, Weller M, McCray PB Jr, Chiorini J, Maury W. From the Cover: T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus. Proc Natl Acad Sci U S A. 2011 May 17;108(20):8426-31. PMID: 21536871 Featured article.
Brindley MA*, Hunt CL*, Kondratowicz AS, Bowman J, Sinn PL, McCray PB Jr, Quinn K, Weller ML, Chiorini JA, Maury W. Tyrosine kinase receptor Axl enhances entry of Zaire ebolavirus without direct interactions with the viral glycoprotein. Virology. 2011 Jul 5;415(2):83-94. PMID: 21529875 (*authors contributed equally)
Oh C, Price J, Brindley MA, Widrlechner MP, Qu L, McCoy JA, Murphy P, Hauck C, Maury W. Inhibition of HIV-1 infection by aqueous extracts of Prunella vulgaris L. Virol J. 2011 Apr 23;8:188. PMID: 21513560
2010
Brindley MA and Plemper RK. Blue Native PAGE and Biomolecular Complementation Reveal a Tetrameric or Higher-Order Oligomer Organization of the Physiological Measles Virus Attachment Protein H. J Virol. 2010 Dec; 84(23):12174-84. PMID: 20861270 Featured article.
2009
Paal T*, Brindley MA*, St Clair C*, Prussia A*, Gaus D, Krumm SA, Snyder JP, Plemper RK. Probing the spatial organization of measles virus fusion complexes. . J Virol. 2009 Oct;83(20):10480-93. PMID: 19656895 (*authors contributed equally)
Quinn K, Brindley MA, Weller ML, Kaludov N, Kondratowicz A, Hunt CL, Sinn PL, McCray PB Jr, Stein CS, Davidson BL, Flick R, Mandell R, Stapleton W, Maury W, Chiorini JA. Rho GTPases Modulate Entry of Ebola and Vesicular Stomatitis Pseudotyped Vectors. J Virol. 2009 Oct;83(19):10176-86. PMID: 19625394
Maury W, Price JP, Brindley MA, Oh CS, Neighbors J, Wiemer D, Wills N, Carpenter S, Hauck C, Murphy PA, Widrlechner MP, Delate K, Kumar G, Kraus GA, Rizshsky L and Nikolau B. Identification of light-independent inhibition of human immunodeficiency virus-1 infection through bioguided fractionation of Hypericum perforatum. Virol J. 2009 Jul 13;6:101. PMID: 19594941
Brindley MA, Widrlechner M, McCoy J, Murphy P, Hauck C, Maury W. Inhibition of lentivirus replication by aqueous extracts of Prunella vulgaris. Virol. J. 2009 Jan 20;6(1):8. PMID: 19154592
2008
Brindley MA, Zhang B, Montelero RC, Maury W. An equine infectious anemia virus variant superinfects cells through novel receptor interactions. J Virol. 2008 Oct;82(19):9425-32. PMID: 18667522
Tallmadge RL, Brindley MA, Salmans J, Mealey RH, Maury W, Carpenter S. Development and characterization of an equine infectious anemia virus Env pseudotyped reporter virus. Clin Vaccine Immunol. 2008 Jul;15(7):1138-40. PMID: 18448619
Brindley MA, Maury W. Equine infectious anemia virus entry occurs through clathrin-mediated endocytosis. J Virol. 2008 Feb;82(4):1628-37. PMID: 18057237
2007
Brindley MA, Hughes L, Ruiz A, McCray PB Jr, Sanchez A, Sanders DA, Maury W. Ebolavirus glycoprotein 1: identification of residues important for binding and post binding events. J Virol. 2007 Jul;81(14):7702-9. PMID: 17475648
2005
Brindley MA, Maury W. Endocytosis and a low-pH step are required for productive entry of equine infectious anemia virus. J Virol. 2005 Dec;79(23):14482-8. PMID: 16282447
2002
Lyubchenko YL, Shlyakhtenko LS, Binus M, Gaillard C, Strauss F. Visualization of hemiknot DNA structure with an atomic force microscope. Nucleic Acids Res. 2002 Nov 15;30(22):4902-9. PMID: 12433993